A charming yellow historic home with white trim and a wraparound porch sits beneath a large tree on a quiet street in Charleston, surrounded by colorful neighboring houses and greenery.

8 Boutique Vacation Rentals in Charleston, SC

Published: May 17, 2025

Sometimes, a vacation to a new city is just as relaxing as a beach getaway. In fact, a trip to the heart of Charleston, South Carolina might be just what you need to unwind from the daily grind.

With eight stunning boutique homes in downtown Charleston, Stay Duvet pulls out all the stops for their guests. You can count on gorgeous layouts and all the amenities you expect of a luxury accommodation.

Escape everyday life with one of these Charleston vacation rentals:

1. Mint Julep

A modern backyard oasis features a rectangular pool surrounded by palm trees, cushioned lounge chairs with umbrellas, a corner outdoor sofa, and a barbecue grill area.

Find your own private paradise in the heart of Charleston with a stay at Mint Julep. With space for up to 12 guests, high-end appliances, and a sparkling pool, you'll love vacationing at this gorgeous rental.

While you may never want to leave the private pool, you'll also have access to an indoor fitness studio, spa therapies, and complimentary social events at the Wonderer Charleston. A stay at Mint Julep is the perfect blend of serenity and socialization!

2. Phil's Place

A cozy screened-in porch features a wooden dining table with patterned chairs, surrounded by white railings and palm trees in the backyard.

Phil's Place is a cozy coastal retreat in the Mount Pleasant area. Up to eight guests will love the open floor plan, complete with plush furniture, a fully-equipped kitchen, and an outdoor grill. If you choose to venture outside your deluxe accommodation, you can take advantage of resort-style amenities at The Wonderer Charleston, a private membership club downtown.

Whether you cozy up at Phil's Place or take a trip into the city, you'll enjoy modern comforts as well as access to nearby beaches.

3. Honeydew

A chic living room features exposed brick walls, a white fireplace with a mounted TV, tan leather chairs, a velvet navy couch, and large windows with views of palm trees and colorful buildings.

The Honeydew is where modern convenience meets rustic charm. This amazing boutique home is one of our favorite Charleston SC vacation rentals for good reason! It's perfect for smaller groups of four guests and features original hardwood floors, sophisticated high ceilings, and luxurious beds you'll never want to leave.

You'll be in historic downtown, right in the center of it all, with access to spas, live music, shopping, and restaurants. Not to mention, you're never more than a short drive to the beach!

4. The Sunsetter

A bright and inviting living room features a mix of cozy seating including a blue couch, tan loveseat, and gray armchair, with large windows letting in natural light and views of colorful buildings outside.

Get a true Charleston experience at the Sunsetter. This historic home is located downtown, but doesn't skimp on outdoor space. You'll enjoy a spacious porch to soak up the sun, as well as a recently updated kitchen.

This rental has room for eight guests, and no matter which bedroom you make your own, you'll have freshly laundered linens and resort-style amenities. In addition to access to a private membership club, you'll also enjoy the convenience of private parking spaces!

5. Bee and Blossom

An elegant living room features two teal velvet sofas, a white fireplace, a gold chandelier, and patterned blue wallpaper with gold accents, creating a luxurious and classic atmosphere.

Not all Charleston vacation rentals are the same, and no place embodies unique style quite like Bee and Blossom. This magical home sleeps 16 guests and boasts a prime location--you'll be close to dining, historical attractions, and sandy beaches.

Bee and Blossom has an open floor plan characteristic of modern living, but the design details create a whimsical space unlike any other. Cozy up in a four-poster bed or take in the beautiful city from the home's two-level porch and courtyard.

6. The Indigo House

A colorful bedroom features a modern green paneled accent wall, vibrant red and pink botanical wallpaper, a platform bed with a tall velvet headboard, and two small lamps on either side.

Here's another boutique home with stand-out design features--the Indigo House. With patterned wallpaper, a lavender kitchen, and comfy accent chairs, this Charleston vacation rental is perfect for travelers who want a little something different. With four bedrooms, the Indigo House sleeps up to 10 guests and is located just a few minutes from some of the city's best restaurants.

You'll love getting some sun in the private fairytale garden or stopping by the off-site guest resort. When you book the Indigo House, you'll be glad you didn't settle for typical Charleston vacation rentals!

7. The Tango

A bright, airy bedroom with vaulted ceilings and exposed wood beams features a white bed, neutral-toned furnishings, black and white patterned pillows, and natural textures like woven rugs and light fixtures.

Quiet luxury is the name of the game at the Tango. This newly renovated one-bedroom studio is ideal for a couple's getaway or solo travel moment. The fresh white linens make for an airy and relaxing atmosphere, while a dedicated parking space ups the convenience factor.

Guests at the Tango enjoy a prime location, just 20 minutes away from the airport and within a stone's throw of the city's best attractions. Within a few minutes, you could be getting a tan at the beach or feeling wanderlust in the historic district.

8. The Place to Be

A modern kitchen and dining area features a bold green island with wood barstools, a round dining table with rattan-back chairs, open shelving, and stylish accents like a black fridge and geometric wallpaper.

Southern charm with a modern twist? Sign us up! They don't call it the Place to Be for nothing--this beautiful boutique home has room for up to eight guests and boasts all kinds of amenities. You'll have access to an elegant dining area, top-of-the-line kitchen appliances, and peaceful bedrooms. What's more, historic Charleston is right at your doorstep!

Spend the day relaxing in bed, or travel down the cobblestone streets for a look at what makes this city a favorite destination. After a day of seeing the sights, come back to the Place to Be for a soak in the freestanding tub!

Knowing where to stay in Charleston couldn't be easier with our partner Stay Duvet. Once you take a look at their magical properties, you'll never want to settle for a run-of-the-mill hotel room again. Check out their Charleston rentals and start planning your ideal getaway!

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